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Micronutrients/Neuropathy
Study
A
study testing the effectiveness of a high-dose formulation
of micronutrients (vitamins and minerals) in pain reduction,
and nerve protection & strengthening, in those suffering
from peripheral neuropathy resulting from treatment with either
ddI or d4T.
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Peripheral
neuropathy occurs in more than 10% of patients beginning
antiretroviral therapy with either d4T or ddI. Similar
neuropathic conditions have been reported to experience
some benefit on a similar regimen of high-dose micronutrients.
There is evidence to suggest that such treatment will
be non-toxic with few or no side effects.
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Objective
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To
determine whether a specific combination of high-dose
micronutrients (vitamins and minerals) is effective
in reducing pain resulting from peripheral neuropathy,
and effective in strengthening and protecting nerves
at risk from damage.
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A
double-blind, placebo-controlled 12 -week pilot study
of high dose micronutrients.
Study volunteers will be compensated up to $25 per
visit for their inconvenience.
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Inclusion
Criteria
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- HIV-positive
male or female at least 18 years old
- Currently
taking d4T and/or ddI
- T-cell
count greater than or equal to 100
- Diagnosis
of peripheral neuropathy within the last 12 months
(must bring written documentation to screening visit).
- If
female, not pregnant and willing to use a barrier
method of contraception throughout the study
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Status
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Enrolling
--
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For
more information about participating in this study
in the Los Angeles area, please call 310/358.2429
or e-mail Corie Castro at
ccastro@aidsresearch.org
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We
encourage participation by women and people of color.
This
ad was reviewed and approved by the AIDS ReSearch Alliance
Institutional Review Board in January, 2003.
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