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The
standard dose of Agenerase requires individuals
to take large numbers of pills. Norvir has been
shown to lengthen the time that Agenerase stays
in the blood. In theory, that might mean that Norvir
can increase the potency of a small amount of Agenerase
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Objective
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To
determine whether the addition of low dose Norvir
to lower, experimental dose Agenerase will be as
effective as the higher, standard dose of Agenerase
. |
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Volunteers
will be assigned to one of two study groups:
Group
1: Volunteers will receive 1200 mg of Agenerase
. At least 2 additional anti-HIV medications will be
prescribed.
Group
2: Volunteers will receive 600 mg of Agenerase
and 100 mg of Norvir. At least 2 additional anti-HIV
medications will be prescribed.
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Inclusion
Criteria
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Two kinds of volunteers are needed:
- Volunteers
who have taken or are taking anti-HIV medications.
- Volunteers
who have never taken anti-HIV medications before.
T-cell count greater than 50
HIV+ male or female
If female, not pregnant and willing to use contraceptives
for the duration of the study.
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Status
__
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Enrolling
--
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For
more information about participating in this study
in the Los Angeles area, please call 310/358.2429
or e-mail Corie Castro at ccastro@aidsresearch.org
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We
encourage participation by women and people of color.
This
ad was reviewed and approved by the AIDS Research Alliance
Institutional Review Board in December, 2000.
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