Clinical Trials
Scientific Research [click here]
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Clinical trials [click here]
Research & Clinical Trials at ARA |
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STUDY & INDICATION |
DESCRIPTION |
STATUS |
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Pre-Clinical &
Basic Research
AIDS Research Alliance (ARA) |
ARA is engaged in a number of ongoing preclinical
and basic research projects. For example, the prostratin
update (page 24) outlines important progress in
the development of prostratin as an anti-HIV drug targeting
viral reservoirs. |
Study Ongoing |
New Investigational
Anti-HIV drug
Investigational
Integrase Inhibitor
Major Pharmaceutical Co. |
This study compares the safety and activity of an investigational
integrase inhibitor in combination regimens
with optimized background treatments, compared to
optimized background therapy alone in antiretroviral experienced,
HIV-infected volunteers with documented
resistance to one of the antiretroviral drug in each class. |
Enrollment &
Study Ongoing |
New Investigational
Protease Inhibitor
TMC114
Tibotec |
This study compares the efficacy, safety and tolerability
of TMC114/RTV versus LPV/RTV in treatmentexperienced
HIV-1 infected volunteers. |
Enrollment &
Study Ongoing |
New Investigational
Treatment for
HIV-Associated
Neuropathic Pain
Pregabalin A0081066
Pfizer |
This trial investigates the efficacy and safety of pregabalin
(versus placebo) in the treatment of neuropathic
pain in HIV-positive volunteers. |
Enrollment &
Study Ongoing |
New Investigational
Treatment to
Decrease Abdominal
Fat Accumulation
TH9507 (Growth Hormone Analog)
Theratechnologies Inc. |
This study assesses the efficacy and safety of
TH9507, a growth hormone releasing factor analog
in HIV-positive volunteers with excess abdominal
fat accumulation. |
Enrollment &
Study Ongoing |
New Investigational
Test To Measure
Resistance to Anti-HIV
Medications
HIV SpectraPoint
SpectraDigital Corporation |
This Phase I study investigates the efficacy of an
in vitro diagnostic device, HIV SpectraPoint, in HIV -
positive volunteers with prior resistance to antiretroviral
medications. |
Enrollment &
Study Ongoing |
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STUDY & INDICATION |
DESCRIPTION |
STATUS |
Investigational
Supplement for
treatment of Diarrhea
Microbial Food Supplement
AIDS Research Alliance (ARA) |
This study investigates the safety and efficacy of
Bifidobacterium infantis therapy in the treatment of
HIV-1 associated diarrhea. |
Enrollment &
Study Ongoing |
Investigational
HIV-1 Vaccine
Major Pharmaceutical Co. |
This study investigates the safety, tolerability and efficacy
of an investigational HIV-1 vaccine in healthy volunteers
at higher risk of HIV infection. |
Enrollment &
Study Ongoing |
Investigational
HIV-1 Vaccine
Major Pharmaceutical Co. |
This study investigates the safety, tolerability and efficacy
of an investigational HIV-1 vaccine in healthy volunteers
at low risk of HIV infection. |
Enrollment &
Study Ongoing |
New Investigational
Regimen for
HIV-Positive Volunteers
Failing HAARTContaining
Regimen
BMS AI424128
Bristol-Myers Squibb |
This study evaluates 150L substitution among treatment-
experienced HIV-positive volunteers who have
failed Highly Active Antiretroviral Therapy (HAART)
regimens containing Atazanavir (ATV). |
Enrollment &
Study Ongoing |
New Investigational
Anti-HIV Medication
CCR5
Human Genome Sciences, Inc. |
This study evaluates the safety, tolerability, pharmacokinetics,and
pharmacodynamics of CCR5mAb004
(human monoclonal IgG4 antibody to CCR5) in HIV-
1 positive individuals who are not receiving antiretroviral
therapy. |
Enrollment
Pending |
New Investigational
Anti-HIV Medication
Investigational
Integrase Inhibitor
Major Pharmaceutical Co. |
This study compares the safety and activity of an
investigational integrase inhibitor in combination regimens
with two approved antiviral drugs, compared to
a standard 3-drug combination in antiretroviral naïve,
HIV-infected volunteers. |
Enrollment
Complete &
Study Ongoing |
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